Specialists in First-in-Human (FiH) clinical trials, CRS delivers fast, EMA-compliant early-phase drug development services with expert subject recruitment, PK/PD analysis, and dose escalation support.
World leading CRO in infectious and respiratory human challenge trials, offering over 14 validated models, state of the art labs & rapid recruitment.
Phase II–III infectious, respiratory, and cardiometabolic clinical trials across UK and Germany, with expert-led design, rapid recruitment, and advanced diagnostic capabilities.
CRS Clinical Research Services, part of the hVIVO Group, delivers end-to-end clinical pharmacology trial solutions with a focus on early-phase development and therapeutic specialisation.
Data Management and Biostatistics
Comprehensive data management and biostatistics support for clinical trials, ensuring accurate data capture, analysis, and timely, high-quality study results.
Our experienced, GCP-certified medical monitors provide trusted leadership for externally sponsored trials.
Accurate, compliant medical writing for clinical, regulatory, and safety documents - tailored to your needs.
Expert coordination ensuring timely, high-quality project delivery.
Rigorous standards and oversight to ensure compliance and data integrity across all processes.
Reliable clinical trial recruitment with over 400,000 volunteers, advanced CRM technology, and tailored participant matching to accelerate your study success.
Expert regulatory affairs support for seamless drug development, from submission preparation to ongoing trial compliance and final reporting.
World-class in-patient clinical trial sites across the UK and Germany, offering over 150 beds for early-phase, infectious disease, and specialist studies including advanced quarantine, PK/PD, and biosafety capabilities.
Five integrated outpatient clinical trial sites across the UK and Germany, offering over 1,000 weekly participant screenings, on-site IMP administration, and advanced laboratory capabilities.
Expert support in study setup and data analysis.
Optimising clinical development through expert PK/PD analysis and strategic insight across all phases.
Expert CMC support to ensure safe, consistent, and regulatory-ready drug development from concept to market.
Advancing drug candidates with tailored, expertly managed non-clinical development strategies.
Expert regulatory affairs support for seamless drug development, from submission preparation to ongoing trial compliance and final reporting.
Comprehensive preclinical support including drug development planning, PK/PD modeling, translational simulation, and biomarker strategies to accelerate success.
Scientific Consulting & Regulatory Support
Expert scientific and regulatory consulting for vaccine development, infectious disease, and cardiometabolic programs. Strategic planning, compliance audits, and submission support to accelerate success.
Techniques, Technology & Automation
Comprehensive assay platforms including PK/PD, ELISA, ELISpot, RT-qPCR/ddPCR, NGS, microbiome sequencing, and immunoassays. Automated workflows for reproducibility and scalability.
Global sample processing network offering PBMC isolation and downstream analysis for immunology research. GLP/GCP compliant workflows for clinical and translational studies.
Clinical Trial Supplies & Kit Production
Custom clinical trial kits, site training, and investigator support for Phase I–III studies. Bespoke design and RSV stabilization matrix for extended stability.
Bioanalysis & Characterisation Services
Expert bioanalysis and compound characterisation for startups, biotech, and pharma. GLP/GCLP-compliant, FDA/EMA aligned services for drug development.
Assay Development & Validation Services
Expert assay development, customisation and validation for startups, biotech, and pharma. Reliable, fit for purpose from exploratory research through clinical trials.
hVIVO is an industry leader in virology and immunology laboratory services, and has been working in this field as a contract research organisation (CRO) since 1989. Operating as a highly specialised virology, immunology and molecular laboratory, our comprehensive array of services are tailored to support drug and vaccine research & development, and drive innovation in the field of virology.
Ethically approved human biological samples from a UK Registered Research tissue bank. Respiratory pathogen-positive sets and prospective collection for advanced research.
Secure cryostorage solutions under HTA and Home Office Controlled Drugs licenses with full compliance (GMP, GDP & GLP). Long and short-term storage at Room Temperature, -20oC, -80°C and liquid nitrogen for clinical and research samples including compounds and genome libraries.
hVIVO Research Tissue Bank, IRAS ID 331455
Access to high-quality, ethically approved human biological samples is essential for advancing respiratory research and drug development. Our services ensure compliance, reliability, and flexibility, supporting studies from early discovery through clinical phases. With a focus on respiratory pathogens, we provide unique sample sets and prospective collection capabilities to meet your specific research needs.
• Whole Blood
• Serum
• Plasma
• PBMC
• Buffy Coat
• Nasopharyngeal Swabs
• Throat Swabs
• Vagina Swabs
• Rectal Swabs
• Nasal Wick
• Saliva
• Urine
• Nail Clippings
• Hair
• Tears
Research Tissue Bank (RTB) – ethically approved
Longitudinal biofluids from FluA and RSV characterisation studies
Prospective sample collection tailored to your study requirements
We operate under the strict UK ethical and regulatory standards, from collection to biobanking. Our processes guarantee traceability, consent compliance, and quality assurance for every sample provided.
Our Research Biobank approval allows our samples to be utilized in ethically approved projects without further applications.
However if your project needs require expanded scope or new sample collections, our medical writers can help with your application process.


We are GDPR, UKDP compliant organization. Our participant recruitment department manages all patient information.
Samples accompanied by PCR viral titres, antibody titres, donor demographics, symptom diaries etc, collected over multiple timepoints form pre-infection to 28-days post infection (depending on the virus incubation time).
Our human biological samples support a wide range of respiratory research applications:
• Pre-clinical drug discovery and drug development
• Diagnostics development and validation (including new ways to screen for or diagnose disease)
• Biomarkers discovery and validation
• Translational medicine
• In-vitro model development
• UK compliant (collected, processed and stored) samples
• GCLP processing lab
• Access to longitudinal respiratory pathogen (flu A and RSV only)-positive samples
• Custom prospective collection for specific research needs
• Samples collected daily at London sites, with the ability to arrange same day shipment
• Reliable quality control and documentation
• Expert Consultation to define sample requirements
• Embedded ethical and regulatory review

Sign up to our emails and follow us on social media to keep up to date with hVIVO.