Specialists in First-in-Human (FiH) clinical trials, CRS delivers fast, EMA-compliant early-phase drug development services with expert subject recruitment, PK/PD analysis, and dose escalation support.
World leading CRO in infectious and respiratory human challenge trials, offering over 14 validated models, state of the art labs & rapid recruitment.
Phase II–III infectious, respiratory, and cardiometabolic clinical trials across UK and Germany, with expert-led design, rapid recruitment, and advanced diagnostic capabilities.
CRS Clinical Research Services, part of the hVIVO Group, delivers end-to-end clinical pharmacology trial solutions with a focus on early-phase development and therapeutic specialisation.
Data Management and Biostatistics
Comprehensive data management and biostatistics support for clinical trials, ensuring accurate data capture, analysis, and timely, high-quality study results.
Our experienced, GCP-certified medical monitors provide trusted leadership for externally sponsored trials.
Accurate, compliant medical writing for clinical, regulatory, and safety documents - tailored to your needs.
Expert coordination ensuring timely, high-quality project delivery.
Rigorous standards and oversight to ensure compliance and data integrity across all processes.
Reliable clinical trial recruitment with over 400,000 volunteers, advanced CRM technology, and tailored participant matching to accelerate your study success.
Expert regulatory affairs support for seamless drug development, from submission preparation to ongoing trial compliance and final reporting.
World-class in-patient clinical trial sites across the UK and Germany, offering over 150 beds for early-phase, infectious disease, and specialist studies including advanced quarantine, PK/PD, and biosafety capabilities.
Five integrated outpatient clinical trial sites across the UK and Germany, offering over 1,000 weekly participant screenings, on-site IMP administration, and advanced laboratory capabilities.
Expert support in study setup and data analysis.
Optimising clinical development through expert PK/PD analysis and strategic insight across all phases.
Expert CMC support to ensure safe, consistent, and regulatory-ready drug development from concept to market.
Advancing drug candidates with tailored, expertly managed non-clinical development strategies.
Expert regulatory affairs support for seamless drug development, from submission preparation to ongoing trial compliance and final reporting.
Comprehensive preclinical support including drug development planning, PK/PD modeling, translational simulation, and biomarker strategies to accelerate success.
Scientific Consulting & Regulatory Support
Expert scientific and regulatory consulting for vaccine development, infectious disease, and cardiometabolic programs. Strategic planning, compliance audits, and submission support to accelerate success.
Techniques, Technology & Automation
Comprehensive assay platforms including PK/PD, ELISA, ELISpot, RT-qPCR/ddPCR, NGS, microbiome sequencing, and immunoassays. Automated workflows for reproducibility and scalability.
Global sample processing network offering PBMC isolation and downstream analysis for immunology research. GLP/GCP compliant workflows for clinical and translational studies.
Clinical Trial Supplies & Kit Production
Custom clinical trial kits, site training, and investigator support for Phase I–III studies. Bespoke design and RSV stabilization matrix for extended stability.
Bioanalysis & Characterisation Services
Expert bioanalysis and compound characterisation for startups, biotech, and pharma. GLP/GCLP-compliant, FDA/EMA aligned services for drug development.
Assay Development & Validation Services
Expert assay development, customisation and validation for startups, biotech, and pharma. Reliable, fit for purpose from exploratory research through clinical trials.
hVIVO is an industry leader in virology and immunology laboratory services, and has been working in this field as a contract research organisation (CRO) since 1989. Operating as a highly specialised virology, immunology and molecular laboratory, our comprehensive array of services are tailored to support drug and vaccine research & development, and drive innovation in the field of virology.
Ethically approved human biological samples from a UK Registered Research tissue bank. Respiratory pathogen-positive sets and prospective collection for advanced research.
Secure cryostorage solutions under HTA and Home Office Controlled Drugs licenses with full compliance (GMP, GDP & GLP). Long and short-term storage at Room Temperature, -20oC, -80°C and liquid nitrogen for clinical and research samples including compounds and genome libraries.
Respiratory Syncytial Virus (RSV) is a common, highly contagious respiratory virus that infects the lungs and airways. While RSV often causes mild, cold-like symptoms in healthy adults, it can lead to severe lower respiratory tract disease in vulnerable populations—particularly infants, young children, older adults, and immunocompromised individuals.
High unmet medical need: Until recently, treatment options were limited and largely supportive (e.g. oxygen and fluids), with few targeted therapies available.
Protection of vulnerable populations: Effective vaccines and antivirals can prevent severe disease in infants, reduce hospitalisations in older adults, and protect those at high risk of complications.
Rapid disease progression: RSV can progress quickly to bronchiolitis or pneumonia, making early intervention with antivirals especially valuable.
Global health impact: RSV causes millions of lower respiratory infections annually worldwide, contributing significantly to infant mortality in low- and middle-income countries.
Preparedness and innovation: Advancing RSV vaccines and antivirals strengthens pandemic preparedness and accelerates innovation across respiratory virus research.
Together, preventive vaccines and therapeutic antivirals offer the most effective strategy to reduce RSV transmission, severity, and healthcare burden—making continued investment in RSV research and development essential.


Join our Chief Scientific Officer, Dr Andrew Catchpole, as he takes you behind the science, sharing expert insight into RSV virus isolation, GMP manufacturing, and the robust clinical data underpinning vaccine and antiviral development.
In this exclusive webinar, you’ll learn about:
Proven patient recruitment strategies at hVIVO
End-to-end human challenge trial services, from design to delivery
Advanced specialist laboratory capabilities
RSV-hMPV-PIV trivalent vaccine challenge platform readiness
Strategic clinical isolate selection
Key insights into infection dynamics, virology, and participant symptoms
Comparative data on RSV-B vs RSV-A infection and incidence rates
Contact our team to discuss how our proven expertise and innovative solutions can help accelerate your development goals.
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