The Human Viral Challenge Model with A/PERTH/16/2009 H3N2A systematic analysis from five clinical studies

The human viral challenge model is well established, safe and ideal to study influenza. It allows researchers to illuminate each step of the infection: baseline, peak and return to healthy. It is possible to stipulate each experimental parameter such as virus strain, environment, sampling methods, schedule of intervention and subjects’ demography (young, older, HLA type, pre-challenge immune response).