hVIVO Challenge Models

hVIVO conducts human challenge studies offering services to both pharmaceutical and biotechnology companies using a range of different clinical trial methodologies across differing viral challenges.

Infectious Diseases:

Influenza

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RSV

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HRV

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Malaria

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Respiratory:

Asthma

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COPD

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Chronic/Acute Cough

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Discover more about what we do:

Human Challenge
Full-service Solution

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Laboratory Services

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hVIVO Challenge Models Scientific Papers / Abstracts

SARS-CoV-2 Human Challenge Studies — Establishing the Model during an Evolving Pandemic

Don’t be afraid of the FDA

Rolling Reviews – a useful tool to speed up the regulatory review process

Hot Topics – Vaccine Solutions for Tropical Diseases

Accelerated regulatory pathway for pandemic vaccines

ERS International Congress 2020 Presentation: Experimental Respiratory Syncytial Virus Infection in Adults 60-75 years

Temporal relationships of cytokines, chemokines and cellular biomarkers during Human Rhinovirus (HRV) infection in asthmatics

A Key Endpoint in Viral Challenge Models of Asthma Exacerbations

Pre-existing NP specific T-cell response correlates with reduction of symptoms in a human influenza challenge model

THE HUMAN VIRAL CHALLENGE MODEL WITH A/PERTH/16/2009 H3N2A SYSTEMATIC ANALYSIS FROM FIVE CLINICAL STUDIES