Open Orphan plc changed its name to hVIVO plc on 26 October 2022, learn more here.

Articles & Research
from hVIVO

Advantages to Centralising Laboratory Services at hVIVO

Clinical field studies are a critical part of the drug development and approval process. They are conducted to evaluate the safety, immunogenicity, and efficacy of a new drug. These studies...

EMA’s updated guideline to include broader coverage on Human Challenge Trials

Advantages of Human Challenge Studies (Part 1)

Human challenge studies or controlled human infection model (CHIM) studies are Phase Ib or Phase IIa clinical trials, in which study participants, i.e. healthy volunteers, are deliberately exposed to infectious...

Accelerated regulatory pathways: Vaccines for tropical diseases

Human Clinical Trials: A Tool in the Fight Against Infectious Diseases

International Clinical Trials, Autumn 2022, pages 94-97. © Samedan Ltd

RSV Vaccines/Prophylactics: Key learning from the RSV challenge model and efficacy of vaccines

Initial characteristics of respiratory viruses in symptomatic subjects during the pandemic, a cohort study

Immunomodulators and treatment of disease in the influenza human challenge model

Human Challenge Studies: Their Conduct and Safety Aspects

If there would be a survey of 100 clinical research professionals either from CRO or from Pharma/Biotech industry to explain what a human challenge study is, the most common answer...

Scientific Paper

Treatment with the P2X3-Receptor Antagonist Gefapixant for Acute Cough in Induced Viral Upper Respiratory Tract Infection: A Phase 2a, Randomized, Placebo-Controlled Trial