Open Orphan plc changed its name to hVIVO plc on 26 October 2022, learn more here.

Articles & Research
from hVIVO

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge

hLab – Virology Laboratory Services

The annual challenge of the global health community is progressing innovative products (vaccines, antiviral drugs, immunomodulators) for the control of infections of significant disease burden in a timely manner at...

Human Challenge Trials as a tool in raising funding

Introduction challenge trials In human challenge studies (HCT) or Controlled Human Infection Models (CHIM), healthy volunteers are administered a pathogenic or virulent strain of a challenge agent, which can be...

SARS-CoV-2 Human Challenge Studies — Establishing the Model during an Evolving Pandemic

Don't be afraid of the FDA

Rolling Reviews – a useful tool to speed up the regulatory review process

Rolling reviews have been in the media spotlight because of a global need to approve COVID-19 treatments and vaccines quickly. This article provides an overview of how rolling reviews work...

Hot Topics – Vaccine Solutions for Tropical Diseases

COVID-19, caused by the betacoronavirus SARSCoV-2, has emerged from a bat reservoir in temperate China, causing a global pandemic that has resulted in over 1.5 million deaths and 68 million...

Accelerated regulatory pathway for pandemic vaccines

Vaccines form an important part of the combat against the current COVID-19 health crisis. Getting a range of effective vaccines to the market quickly will be essential if we are...

ERS International Congress 2020 Presentation: Experimental Respiratory Syncytial Virus Infection in Adults 60-75 years

hVIVO's presentation during the ERS International Congress 2020 presentation about experimental RSV infection in adults 60-75 years.

Temporal relationships of cytokines, chemokines and cellular biomarkers during Human Rhinovirus (HRV) infection in asthmatics

hVIVO's presentation during the ERS International Congress 2019 presentation about temporal relationships of cytokines, chemokines and cellular biomarkers during HRV infection in asthmatics.